By taxi
It should not take more than 30 minutes to drive to the Los Hotel except in the worst rush hour traffic. If you can negotiate a taxi on arrival, the fare should be about $40, but it is probably easier to arrange a transfer with a driver to meet your train, which you can do here.
By metro
By metro, take the brown circle line from Belorusskaya Metro Station and travel clockwise two stops to Prospekt Mira. Change to the orange line and travel north six stops to Babushkinskaya. From there it is around 2 km to the Los Hotel. Exit the station from the front of the train and bear right out of the underpass to find the stop for the No. 605 bus. This will take you to Chelyuskinskaya Ulitsa Meditsinskiy Kolledzh Bus Stop, about 200m from the Los Hotel.