The fastest way to reach the Kremlin from the Marco Polo Presnja Hotel is to take the metro from Chekhovskaya (around ten minutes' walk from the hotel on Pushkinskaya Ploshchad) and travel south on the gray line one stop to Borovitskaya, which is less than five minutes' walk from the Kremlin.
Alternatively, you can walk all the way from the hotel in just over 20 minutes. Turn left out of the hotel and take the first right onto Ulitsa Malaya Bronnaya. Continue to the Boulevard Ring, and turn right along the far side of Nikitskiy Bulvar. Take the second left onto Ulitsa Vozdvizhenka. Follow the street to where it ends at the main visitor entrance to the Kremlin.
Alternatively, you can walk all the way from the hotel in just over 20 minutes. Turn left out of the hotel and take the first right onto Ulitsa Malaya Bronnaya. Continue to the Boulevard Ring, and turn right along the far side of Nikitskiy Bulvar. Take the second left onto Ulitsa Vozdvizhenka. Follow the street to where it ends at the main visitor entrance to the Kremlin.