Kursk Station, the Moscow terminal for trains to/from central Russia (Kursk and Nizhny Novgorod), eastern Ukraine (Donetsk and Kharkiv), and some Sapsan high-speed services from St. Petersburg. It is a little less than 20 km from the Orekhovo Hotel.
By taxi
The drive to the Orekhovo Hotel from the station will take around 30 minutes in reasonable traffic but could be much more at peak times. Taxis should cost around $40, or to save trouble haggling on arrival you can book a transfer with driver to meet your train here.
By metro
From Kurskaya Metro Station, which is connected to the concourse of the mainline station, travel two stops clockwise to Paveletskaya on the brown circle line and change to the dark-green line. Travel six stops south from there to Orekhovo Station, which is less than five minutes on foot from the hotel.